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AD8251:  10 MHz, G = 1, 2, 4, 8 iCMOS® Programmable Gain Instrumentation Amplifier

Product Details

Product Status:Recommended for New Designs

The AD8251 is an instrumentation amplifier with digitally programmable gains that has GΩ input impedance, low output noise, and low distortion, making it suitable for interfacing with sensors and driving high sample rate analog-to-digital converters (ADCs). It has high bandwidth of 10 MHz, low THD of −110 dB, and fast settling time of 785 ns (maximum) to 0.001%. Offset drift and gain drift are guaranteed to 1.8 μV/°C and 10 ppm/°C, respectively, for G = 8. In addition to its wide input common voltage range, it boasts a high common-mode rejection of 80 dB at G = 1 from dc to 50 kHz. The combination of precision dc performance coupled with high speed capabilities makes the AD8251 an excellent candidate for data acquisition. Furthermore, this monolithic solution simplifies design and manufacturing and boosts performance of instrumentation by maintaining a tight match of internal resistors and amplifiers.

The AD8251 user interface consists of a parallel port that allows users to set the gain in one of two different ways (see Figure 1 in data sheet for the functional block diagram). A 2-bit word sent via a bus can be latched using the WR input. An alternative is to use transparent gain mode where the state of logic levels at the gain port determines the gain.

The AD8251 is available in a 10-lead MSOP package and is specified over the −40°C to +85°C temperature range, making it an excellent solution for applications where size and packing density are important considerations.


  • Data acquisition
  • Biomedical analysis
  • Test and measurement

    • Small package: 10-lead MSOP
    • Programmable gains: 1, 2, 4, 8
    • Digital or pin-programmable gain setting
    • Wide supply: ±5 V to ±15 V
    • Excellent dc performance
      High CMRR: 98 dB (minimum), G = 8
      Low gain drift: 10 ppm/°C (maximum)
      Low offset drift: 1.8 μV/°C (maximum), G = 8

    Excellent ac performance

    • Fast settling time: 785 ns to 0.001% (maximum)
    • High slew rate: 20 V/μs (minimum)
    • Low distortion: −110 dB THD at 1 kHz,10 V swing
    • High CMRR over frequency: 80 dB to 50 kHz (minimum)
    • Low noise: 18 nV/√Hz, G = 10 (maximum)
    • Low power: 4 mA

    Functional Block Diagram for AD8251

    Similar Products

    See the AD8250 or the AD8253 for different gain options.


    Title Content Type File Type
    AD8251: 10 MHz, 20 V/μs, G = 1, 2, 4, 8 iCMOS Programmable Gain Instrumentation Amplifier Data Sheet (Rev B, 11/2010) (pdf, 626 kB) Data Sheets PDF
    A Designer's Guide to Instrumentation Amplifiers (3rd Edition) Design Handbooks HTML
    Auto-Zero Amplifiers  (doc, 75 kB)
    A wide variety of electronic applications, especially those involving very small input signals, require signal paths with very low offset voltage and offset voltage drift over time and temperature.
    Technical Articles DOC
    High-performance Adder Uses Instrumentation Amplifiers
    Make an adder circuit using instrumentation amplifiers to increase input impedance.
    (EDN, 9/3/2009)
    Technical Articles HTML
    Leading Inside Advertorials: Applying Instrumentation Amplifiers Effectively–The Importance of an Input Ground Return  (pdf, 121 kB) Overview PDF
    Leading Inside Advertorials: A Whole New Value Equation for Industrial Designs  (pdf, 157 kB) Overview PDF
    RAQs index Rarely Asked Questions HTML
    Glossary of EE Terms Glossary HTML

    Design Tools,Models,Drivers & Software

    Title Content Type File Type
    AD8251 SPICE Macro Model SPICE Models HTML

    Evaluation Kits & Symbols & Footprints

    Evaluation Boards & KitsView the Evaluation Boards and Kits page for documentation and purchasing

    Symbols and Footprints— Analog Devices offers Symbols & Footprints which are compatible with a large set of today’s CAD systems for broader and easier support.

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    Price, packaging, availability

    AD8251 Model Options
    Model Package Pins Temp.
    Price*(100-499) Price*1000 pcs RoHS View PCN/ PDN Check Inventory/
    AD8251ARMZ Status: Production 10 ld MSOP 10 Ind Tube, 50 $5.96 $5.01 Y  Material Info PCN Purchase Sample
    AD8251ARMZ-R7 Status: Production 10 ld MSOP 10 Ind Reel, 1000 - $5.01 Y  Material Info PCN Purchase
    AD8251ARMZ-RL Status: Production 10 ld MSOP 10 Ind Reel, 3000 - $5.01 Y  Material Info PCN Purchase
    Price Table Help

    The USA list pricing shown is for BUDGETARY USE ONLY, shown in United States dollars (FOB USA per unit for the stated volume), and is subject to change. International prices may differ due to local duties, taxes, fees and exchange rates. For volume-specific price or delivery quotes, please contact your local Analog Devices, Inc. sales office or authorized distributor. Pricing displayed for Evaluation Boards and Kits is based on 1-piece pricing.

    AD8251 Evaluation Board
    Model Description Price RoHS View PCN/ PDN Check Inventory/
    AD8251-EVALZ Status: Production Evaluation Board $101.15 Yes -

    Pricing displayed is based on 1-piece. The USA list pricing shown is for budgetary use only, shown in United States dollars (FOB USA per unit), and is subject to change. International prices may vary due to local duties, taxes, fees and exchange rates.

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