Features and Benefits

Analog input/output
  • 16-bit, 400 kSPS ADC
  • Voltage, current, and impedance measurement capability
    • Internal/external current and voltage channels
    • Ultralow leakage switch matrix and input mux
    • Input buffers, programmable gain amplifier
Voltage DACs
  • 2 dual output VDACs
    • Output range 0.2 V to 2.4 V (±2.2 V voltage potential to
    • sensor)
    • 2 bias potentiostat and TIA amplifiers
      • Ultralow power, 1 μA per DAC
  • One high speed 12-bit VDAC
    • Output range to sensor ±607 mV
    • High speed TIA for impedance measurements
    • Programmable gain amplifier on output
Amplifiers, accelerators, and references
  • 2 low power, low noise amplifiers
    • Suitable for potentiostat bias in electrochemical sensing
  • 2 low power, low noise TIAs
    • Suitable for measuring sensor current output
      • ±0.00005 µA to ±3000 µA range
    • Programmable load and gain resistors
  • Analog hardware accelerators
    • DDS waveform generator
    • DFT and digital filters
  • 2.5 V and 1.82 V on-chip, precision voltage references

Internal temperature sensor, ±2°C accurate

Impedance measurement range of <1 Ω to 10 MΩ,  0.016 Hz to 200,000 Hz

Voltammetry scan rate up to 2000 steps per second

  • 26 MHz ARM Cortex-M3 processor
  • Serial wire port supports code download and debug
  • 128 kB flash/64 kB of SRAM
  • Hardware CRC with programmable polynomial generator
  • Read/write protection of user flash
On-chip peripherals
  • UART, I2C, and SPI serial input/output
  • Up to 17 GPIO pins
    • External interrupt option
  • General-purpose, wake-up, and watchdog timers
  • 2.8 V to 3.6 V supply and active measurement range
  • Power-supply monitor
  • Active current consumption 30 μA/MHz for digital part
  • Hibernate with bias to external sensor, 8.5 μA
  • Shutdown mode with no SRAM retention, 2 μA
Targetted at Functional Safety Applications
  • Contact ADI for documentation and for more details
Packages and temperature range
  • 6 mm × 5 mm, 72-lead LGA package
  • Fully specified for −40°C to +85°C ambient operation

Product Details

The ADuCM355 is an on-chip system designed to control and measure electrochemical and biosensors. The ADuCM355 is an ultralow power mixed-signal microcontroller based on the ARM®Cortex-M3 processor. It is designed with current, voltage, and impedance measurement capability.

The ADuCM355 features a 16-bit, 400 kSPS multichannel successive approximation register (SAR) analog-to-digital converter (ADC) with input buffers, built in anti-alias filter and programmable gain amplifier (PGA). The current inputs include three trans-impedance amplifiers (TIA) with programmable gain and load resistors for measuring different sensor types. The analog front end (AFE) also contains two more low power amplifiers designed specifically for potentiostat capability to maintain a constant bias voltage to an external electrochemical sensor. The noninverting inputs of these two amplifiers are controlled by on-chip dual output digital-to-analog converters (DAC). The analog outputs include another high speed DAC and output amplifier designed to generate an ac signal.

The ADC is capable of operating at conversion rates up to 400 kSPS with an input range of ±0.9 V. An input mux before the ADC allows the user to select an input channel for measurement. These input channels include three external current inputs, multiple external voltage inputs, and internal channels. The internal channels allow diagnostic measurements of the internal supply voltages, die temperature, and reference voltages.

Two of the three voltage DACs are dual output, 12-bit string DACs. One output per DAC controls the noninverting input of a potentiostat amplifier, and the other controls the noninverting input of the TIA.

The third DAC (sometimes referred to as the high speed DAC) is designed for the high power TIA for impedance measurements. Its output frequency range is up to 200 kHz.

A precision 1.82 V and 2.5 V on-chip reference source is available. The internal ADC and VDAC circuits use this on-chip reference source to ensure low drift performance for all of these peripherals.

The ADuCM355 integrates a 26 MHz ARM Cortex-M3 processor. It is a 32-bit reduced instruction set computer (RISC) machine, offering up to 32.5 DMIPS peak performance. The ARM Cortex-M3 processor also has a flexible multichannel direct memory access controller (DMA) supporting serial peripheral interface (two independent SPI ports), universal asynchronous receiver/transmitter (UART), and I2C communication peripherals. The ADuCM355 has 128 kB of nonvolatile flash/EE memory and 64 kB of SRAM integrated on-chip.

The digital processor subsystem is clocked from a 26 MHz on-chip oscillator. This is the source of the main digital die system clock. Optionally, a 26 MHz PLL can be used as the digital system clock. This clock can be internally subdivided so that the processor operates at a lower frequency and saves power. A low power internal 32 kHz oscillator is available and can clock the timers. The ADuCM355 includes three general-purpose timers, a wake-up timer (which can be used as a general-purpose timer), and a system watchdog timer.

The analog subsystem has a separate 16 MHz oscillator used to clock the ADC, DACs and other digital logic on the analog die. The analog die also contains a separate 32 kHz, low power oscillator to clock a watchdog timer on the low voltage die. Both the 32 kHz oscillator and this watchdog are independent from the digital die oscillators and system watchdog timer.

A range of communication peripherals can be configured as required in a specific application. These peripherals include UART, I2C, 2xSPI, and GPIO ports. The GPIO, combined with the general-purpose timers, can be combined to generate a pulse width modulation (PWM) type output.

On-chip factory firmware supports in-circuit erasing of user flash triggered via the UART, while nonintrusive emulation and program download are supported via the serial wire debug port (SW-DP) interface.

The ADuCM355 operates from 2.8 V to 3.6 V supply and is specified over a temperature range of −40°C to +85°C. The chip is packaged in a 72-lead 6 mm × 5 mm land grid array (LGA) package.


  • Gas detection
  • Food quality
  • Environmental sensing (air, water, soil)
  • Blood glucose meters
  • Life sciences and biosensing analysis
  • Bioimpedance measurements
  • General Amperometry, voltammetry, and impedance spectroscopy functions

Product Lifecycle icon-recommended Pre-Release

This product is new and engineering validation may still be underway. Quantities may be limited and design specifications may change while we ready the product for release to production.

Evaluation Kits (1)

Reference Designs (2)

Design Resources

ADI has always placed the highest emphasis on delivering products that meet the maximum levels of quality and reliability. We achieve this by incorporating quality and reliability checks in every scope of product and process design, and in the manufacturing process as well.  "Zero defects" for shipped products is always our goal.


ADUCM355 Discussions

RE: EVAL-CN0429-EBZ not displaying correct values.
1 week(s) ago in Reference Circuits
RE: EVAL-CN0429-EBZ not displaying correct values.
1 week(s) ago in Reference Circuits
RE: EVAL-CN0429-EBZ not displaying correct values.
1 week(s) ago in Reference Circuits
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Evaluation Boards Pricing displayed is based on 1-piece.
Pricing displayed is based on 1-piece. The USA list pricing shown is for budgetary use only, shown in United States dollars (FOB USA per unit), and is subject to change. International prices may vary due to local duties, taxes, fees and exchange rates.