Alternative Parts


Features and Benefits

  • Micropower, 85 μA maximum supply current
  • Wide power supply range
    (+2.2 V to ±18 V)
  • Easy to use
    Gain set with one external resistor
    Gain range 5 (no resistor) to 1000
  • Higher performance than discrete designs
  • Rail-to-rail output swing
  • High accuracy dc performance
    0.03% typical gain accuracy (G = +5) (AD627A)
    10 ppm/°C typical gain drift (G = +5)
    125 μV maximum input offset voltage (AD627B dual supply)
    200 μV maximum input offset voltage (AD627A dual supply)
  • 1 μV/°C maximum input offset voltage drift (AD627B)
    3 μV/°C maximum input offset voltage drift (AD627A) 
  • Noise: 38 nV/√Hz RTI noise @ 1 kHz (G = +100)
  • Excellent ac specifications
    AD627A: 77 dB minimum CMRR
    (G = +5)
    AD627B: 83 dB minimum CMRR
    (G = +5)
    80 kHz bandwidth (G = +5)
    135 μs settling time to 0.01%
    (G = +5, 5 V step)

Product Details

The AD627 is an integrated, micropower instrumentation amplifier that delivers rail-to-rail output swing on single and dual (+2.2 V to ±18 V) supplies. The AD627 provides excellent ac and dc specifications while operating at only 85 μA maximum.

The AD627 offers superior flexibility by allowing the user to set the gain of the device with a single external resistor while con-forming to the 8-lead industry-standard pinout configuration. With no external resistor, the AD627 is configured for a gain of 5. With an external resistor, it can be set to a gain of up to 1000.

A wide supply voltage range (+2.2 V to ±18 V) and micropower current consumption make the AD627 a perfect fit for a wide range of applications. Single-supply operation, low power consumption, and rail-to-rail output swing make the AD627 ideal for battery-powered applications. Its rail-to-rail output stage maximizes dynamic range when operating from low supply voltages. Dual-supply operation (±15 V) and low power consumption make the AD627 ideal for industrial applications, including 4 to 20 mA loop-powered systems.

The AD627 does not compromise performance, unlike other micropower instrumentation amplifiers. Low voltage offset, offset drift, gain error, and gain drift minimize errors in the system. The AD627 also minimizes errors over frequency by providing excellent CMRR over frequency. Because the CMRR remains high up to 200 Hz, line noise and line harmonics are rejected.

The AD627 provides superior performance, uses less circuit board area, and costs less than micropower discrete designs.


  • 4 mA to 20 mA loop-powered applications
  • Low power medical instrumentation—ECG, EEG
  • Transducer interfacing
  • Thermocouple amplifiers
  • Industrial process controls
  • Low power data acquisition
  • Portable battery-powered instruments

Product Lifecycle icon-recommended Production

At least one model within this product family is in production and available for purchase. The product is appropriate for new designs but newer alternatives may exist.

Evaluation Kits (1)

Tools & Simulations

In-Amp Diamond Plot Tool

The Diamond Plot Tool is a web application that generates a configuration-specific Output Voltage Range vs. Input Common-Mode Voltage graph, also known as the Diamond Plot, for Analog Devices Instrumentation Amplifiers. Based on user inputs such as supply voltage, gain, and input signal range, the tool detects saturation and recommends in-amps for which the input signal is in-range and the configuration is valid. Avoid saturation, find the best in-amp for your design, and save time.

In Amp Diamond Tool

Design Tools

In-Amp Error Calculator

These tools will help estimate error contributions in your instrumentation amplifier circuit. It uses input parameters such as temperature, gain, voltage input, and source impedance to determine the errors that can contribute to your overall design.

Design Resources

ADI has always placed the highest emphasis on delivering products that meet the maximum levels of quality and reliability. We achieve this by incorporating quality and reliability checks in every scope of product and process design, and in the manufacturing process as well.  "Zero defects" for shipped products is always our goal.

PCN-PDN Information

Sample & Buy

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Evaluation Boards

Pricing displayed is based on 1-piece.

Up to two boards can be purchased through To order more than two, please purchase through one of our listed distributors.

Pricing displayed is based on 1-piece. The USA list pricing shown is for budgetary use only, shown in United States dollars (FOB USA per unit), and is subject to change. International prices may vary due to local duties, taxes, fees and exchange rates.